We have another cure!

Living the Scientific Life (Scientist, Interrupted): Bone Hormone Linked to Obesity and Type 2 Diabetes

Even though bones seem to be metabolically inactive structures, nothing could be further from the truth. In fact, bones are rebuilt constantly through the action of cells known as osteoblasts while old bone is destroyed by other cells known as osteoclasts. Bones also produce red and white blood cells, help maintain blood pH and store calcium. However, exciting new research has shown that bones also act as an endocrine organ. Not only do bones produce a protein hormone, osteocalcin (pictured), that regulates bone formation, but this hormone also protects against obesity and glucose intolerance by increasing proliferation of pancreatic beta cells and their subsequent secretion of insulin. Osteocalcin was also found to increase the body’s sensitivity to insulin and as well as reducing its fat stores.

In other words, we’ve cured diabetes yet again!  Someone get out the score card and let me know how many cures this makes for the calendar year 2007, please.

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